Aging2Cancer is a comprehensive, user-friendly, and interactive web
resource for linking aging to tumor multi-omics data. Aging2Cancer is designed to, a) provide easy access
to publicly available cancer and normal OMICS data with aging information (TCGA, ICGC, and GTEx), b)
allow users to explore the associations between aging and tumor multi-omics characteristics (gene expression
, DNA methylation, single nucleotide variant, and copy number alterations), c) allow users to estimate the
differences in cancer- and aging-related hallmark scores in different age groups, and calculate the
correlation coefficient between gene expression and hallmark scores, d) provide tools to estimate the
differences between age groups for four immune-related modules including immune infiltration, immune
pathway, immune signature, and antitumor immune activity, e) provide plots depicting gene expression
and patient survival information for different age groups. In summary, Aging2Cancer is a valuable
resource for identifying novel biomarkers and will serve as a bridge for linking aging to cancer.
